DPP10 Antibody Summary
| Immunogen |
A synthetic peptide made to residues 521-539 of human DPP10.
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| Localization |
(Subcellular) Type II membrane protein
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| Specificity |
Reacts with residues 521-539 [LKEAILKKKIGKPEIKILH] of human DPP10.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
DPP10
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
This antibody has been tested in Western blot applications using transfected lysates only. No other applications have been tested. Recommended Starting Dilution:* Western blot: 1:500-1:1,000 *The investigator should determine the optimal working dilution for a specific application. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
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| Theoretical MW |
75 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
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| Positive Control |
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Reactivity Notes
Human. Other species not tested.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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| Buffer |
PBS
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| Preservative |
0.02% Sodium Azide
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| Concentration |
1 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for DPP10 Antibody
- dipeptidyl peptidase 10
- Dipeptidyl peptidase IV-related protein 3
- dipeptidyl peptidase like protein 2
- Dipeptidyl peptidase X
- Dipeptidyl peptidase-like protein 2
- dipeptidyl-peptidase 10 (non-functional)
- dipeptidyl-peptidase 10
- DPL2
- DPP X
- DPP10
- DPPY
- DPRP3
- DPRP-3
- DPRP3dipeptidylpeptidase 10
- inactive dipeptidyl peptidase 10
- KIAA1492
Background
A novel gene, DPP10, encodes a homolog of dipeptidyl peptidases (DPPs) that cleave terminal dipeptides from cytokines and chemokines, and it presents a potential new target for asthma therapy. The DPP10 protein shares features with members of the S9B family of DPP serine proteases, which includes DPP4, a widely expressed enzyme that plays a central role in chemokine processing as part of the innate immune system. The locus displays a complex pattern of transcript splicing, with eight alternate first exons; four of which localize within the LD block strongly associated with asthma.