DNA Polymerase iota Antibody

Product: Proflavine (hemisulfate)

DNA Polymerase iota Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 690 and 715 of human DNA polymerase iota using the numbering given in entry NP_009126.1 (GeneID 11201).
Predicted Species
Monkey (100%), Primate (100%). Backed by our 100% Guarantee.
Clonality
Polyclonal
Host
Rabbit
Gene
POLI
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunoprecipitation 2-5 ug/mg lysate
Application Notes
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
83 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publication using
NB100-60668 in the following applications:

  • WB
    1 publication

Reactivity Notes

Human. Based on 100% sequence identity, this antibody is predicted to react with Rhesus Monkey, Gorilla, Chimpanzee, White-tufted-ear marmoset, Crab-eating macaque and Northern white-cheeked gibbon.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for DNA Polymerase iota Antibody

  • DNA polymerase iota
  • EC 2.7.7.7
  • eta2
  • polymerase (DNA directed) iota
  • RAD30 homolog B
  • RAD30Bpolymerase (DNA-directed), iota
  • RAD3OB

Background

Pol Iota is a DNA polymerase involved in DNA repair and translesion DNA synthesis. Pol Iota is a member of the Rad30 family of DNA polymerases which exhibit low fidelity when replicating undamaged DNA, and in this context may play a role in the hypermutation of immunoglobulin genes.

PMID: 23087672