Product: Eprodisate (disodium)
DNA Polymerase delta, catalytic subunit Antibody (607) Summary
| Immunogen |
Recombinant protein encoding amino acids 1-140 of the large subunit of human DNA polymerase d.
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| Localization |
Nuclear
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| Isotype |
IgG
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| Clonality |
Monoclonal
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| Host |
Mouse
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| Gene |
POLD1
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| Purity |
Protein G purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
WB: Detects an approx. 130 kDa protein. Predicted MW is 130 kDa.
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| Positive Control |
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| Publications |
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Reactivity Notes
Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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| Buffer |
PBS (pH 7.2)
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| Preservative |
No Preservative
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| Concentration |
1 mg/ml
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| Purity |
Protein G purified
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Alternate Names for DNA Polymerase delta, catalytic subunit Antibody (607)
- CDC2 homolog
- CDC2
- DNA polymerase delta catalytic subunit
- DNA polymerase subunit delta p125
- DNA-directed polymerase delta 1
- EC 2.7.7.7
- POLD
- polymerase (DNA directed), delta 1, catalytic subunit (125kD)
- polymerase (DNA directed), delta 1, catalytic subunit 125kDa
Background
DNA polymerase d (delta) functions in DNA replication and DNA repair. It also possesses 3 to 5 exonuclease activity. In leading strand synthesis it requires the processivity factor, PCNA. It is also possibly involved in the completion of DNA synthesis during Okazaki fragment elongation following the initiation of synthesis by the DNA polymerase a/primase complex