DEP-1/CD148 Antibody (261922)

Product: Avosentan

DEP-1/CD148 Antibody (261922) Summary

Immunogen
E. coli-derived recombinant human DEP‑1/CD148
Arg997-Ala1337
Accession # Q12913
Specificity
Detects human DEP‑1/CD148.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
PTPRJ
Purity
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • Flow Cytometry 2.5 ug/10^6 cells

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A or G purified from hybridoma culture supernatant
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for DEP-1/CD148 Antibody (261922)

  • CD148 antigen
  • CD148
  • Density-enhanced phosphatase 1
  • DEP1
  • DEP-1
  • DEP1EC 3.1.3.48
  • HPTP eta
  • HPTPeta
  • HPTP-eta
  • human density enhanced phosphatase-1
  • protein tyrosine phosphatase, receptor type, J polypeptide
  • protein tyrosine phosphatase, receptor type, J
  • Protein-tyrosine phosphatase eta
  • Protein-tyrosine phosphatase receptor type J
  • PTPRJ
  • receptor-type tyrosine-protein phosphatase eta
  • R-PTP-ETA
  • R-PTP-J
  • SCC1
  • susceptibility to colon cancer 1, mouse, homolog of

Background

DEP-1 (density enhanced protein tyrosine phosphatase-1), also known as CD148, HPTP-eta, and PTP receptor type J (PTPRJ), is an enzyme that removes phosphate groups covalently attached to tyrosine residues in proteins. DEP-1 is a large glycoprotein expressed on the cell surface at levels that increase with high cell density. DEP-1 is widely expressed in tissues, particularly those forming epithelioid monolayers. In the immune system, DEP-1 is found on all cell lineages with highest expression levels on granulocytes.

PMID: 22894757