Cytokeratin 7 Antibody (KRT7/760 KRT7/903) [FITC] Summary
Immunogen |
Recombinant full-length human KRT7 protein
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Localization |
Cytoplasmic
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Marker |
Glandular and Transitional Epithelial Marker
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Specificity |
It recognizes an intermediate filament protein (IFP) of 55kDa, which is identified as cytokeratin 7. This MAb is highly specific to cytokeratin 7 and shows no cross-reaction with other IFPs. Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. This MAb is highly useful in distinguishing ovarian carcinomas (keratin 7+) from colon carcinomas (keratin 7-).
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Isotype |
IgG
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Clonality |
Monoclonal
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Host |
Mouse
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Gene |
KRT7
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Purity |
Protein A or G purified
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Applications/Dilutions
Dilutions |
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Application Notes |
Optimal dilution of this antibody should be experimentally determined.
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Packaging, Storage & Formulations
Storage |
Store at 4C in the dark.
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Buffer |
PBS
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Preservative |
0.05% Sodium Azide
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Purity |
Protein A or G purified
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Alternate Names for Cytokeratin 7 Antibody (KRT7/760 KRT7/903) [FITC]
- CK7
- CK-7
- cytokeratin 7
- cytokeratin-7
- K2C7
- K7keratin, 55K type II cytoskeletal
- keratin 7
- keratin, type II cytoskeletal 7
- keratin-7
- MGC129731
- MGC3625
- sarcolectin
- SCLkeratin, simple epithelial type I, K7
- type II mesothelial keratin K7
- Type-II keratin Kb7