Cysteine Conjugate beta-Lyase/CCBL1 Antibody (1B12) Summary
| Immunogen |
CCBL1 (AAH33685, 1 a.a. – 374 a.a.) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKVELWP
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| Specificity |
CCBL1 – cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase) (1B12)
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| Isotype |
IgG2a Kappa
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| Clonality |
Monoclonal
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| Host |
Mouse
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| Gene |
CCBL1
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| Purity |
IgG purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
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| Buffer |
PBS (pH 7.4)
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| Preservative |
No Preservative
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| Purity |
IgG purified
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Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Cysteine Conjugate beta-Lyase/CCBL1 Antibody (1B12)
- CCBL1
- Cysteine Conjugate betaLyase
- Cysteine Conjugate beta-Lyase
- cysteine conjugate-beta lyase, cytoplasmic
- cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K
- Cysteine-S-conjugate beta-lyase
- EC 2.6.1.64
- EC 2.6.1.7
- EC 4.4.1.13
- FLJ95217
- Glutamine Transaminase K
- glutamine-phenylpyruvate aminotransferase
- Glutamine–phenylpyruvate transaminase
- GTKMGC29624
- KAT1
- KATI
- KATIbeta-lysase, kidney
- Kyneurenine Aminotransferase I
- kyneurenine aminotransferase
- kyneurenine aminotransferase)
- Kynurenine aminotransferase I
- kynurenine–oxoglutarate transaminase 1
- Kynurenine–oxoglutarate transaminase I
Background
This gene encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq]