Cyclophilin-F Antibody (1F5) Summary
| Immunogen |
Recombinant human PPIF (30-207aa) purified from E. coli (NP_005720).
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| Isotype |
IgG2b Kappa
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| Clonality |
Monoclonal
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| Host |
Mouse
|
| Gene |
PPIF
|
| Purity |
Protein G purified
|
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Applications/Dilutions
| Dilutions |
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| Application Notes |
The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
| Theoretical MW |
22 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4) and 10% Glycerol
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| Preservative |
0.02% Sodium Azide
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| Concentration |
1.0 mg/ml
|
| Purity |
Protein G purified
|
Alternate Names for Cyclophilin-F Antibody (1F5)
- Cyclophilin F
- CYP3FLJ90798
- Cyp-D
- hCyP3
- MGC117207
- mitochondrial
- peptidyl-prolyl cis-trans isomerase, mitochondrial
- peptidylprolyl isomerase F (cyclophilin F)
- peptidylprolyl isomerase F
Background
The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.