Cyclin L2 Antibody Summary
| Immunogen |
The immunogen recognized by this antibody maps to a region between residue 470 and 520 of human cyclin L2 using the numbering given in entry NP_112199.2 (GeneID 81669).
|
| Predicted Species |
Primate (100%), Monkey (100%). Backed by our 100% Guarantee.
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
CCNL2
|
| Purity |
Immunogen affinity purified
|
| Innovators Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
|
Applications/Dilutions
| Dilutions |
|
|
| Publications |
|
Reactivity Notes
Based on 100% sequence identity, this antibody is predicted to react with Gorilla and Chimpanzee
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
TBS and 0.1% BSA
|
| Preservative |
0.09% Sodium Azide
|
| Concentration |
0.2 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for Cyclin L2 Antibody
- ania-6b
- CCNM
- cyclin L2
- cyclin M
- cyclin-L2
- DKFZp761A1210
- DKFZp762O195
- HCLA-ISO
- HLA-ISO
- Paneth cell-enhanced expression protein
- PCEE
- SB138
Background
Cyclin L2 is a member of the cyclin family of regulatory proteins that associate with and activate cyclin-dependent kinases (CDKs) to regulate cell cycle progression and transcription. The hallmark characteristic of cyclins is the periodicity of their expression and activity that is regulated transcriptionally and post-transcriptionally via phosphorylation and ubiquitination. Cyclin L2 is part of a group of cyclins that are involved in transcriptional regulation at the level of RNA transcription, initiation, elongation, and RNA processing. The transcriptional regulating cyclins include cyclin C, H, K, L1, L2, T1, and T2 which associate with CDK7, -8, -9, -10 and -12. Cyclin L2 associates with CDK11 and RNA polymerase II and co-localizes with splicing factors and is implicated to play a role in pre-mRNA splicing. Alternate names for cyclin L2 include cyclin M, paneth cell-enhanced expression protein, CCNM, and CCNL2.