Claudin-5 Antibody Summary
| Immunogen |
Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) (Mouse) (C terminal).
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| Localization |
Cell Membrane
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| Specificity |
Claudin 5
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
CLDN5
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
This product is useful for Immunohistochemistry Paraffin. If a 6mL or 7mL pre-diluted size is purchased this product can be used Neat (without further dilution). Use recommended dilution for the concentrated vials only.
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| Positive Control |
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| Publications |
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Reactivity Notes
Cross-reacts with Human and Mouse.Not yet tested in other species.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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| Buffer |
TBS (pH 7.6) and 1.0% BSA
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| Preservative |
0.1% Sodium Azide
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| Purity |
Immunogen affinity purified
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Alternate Names for Claudin-5 Antibody
- AWAL
- AWALTransmembrane protein deleted in VCFS
- BEC1
- claudin 5
- Claudin5
- Claudin-5
- CLDN5
- CPETRL1
- TMDVCF
- TMVCF1
- TMVCFTMDVCF
- transmembrane protein deleted in velocardiofacial syndrome
Background
Claudin 1-8 proteins are a family of transmembrane proteins associated with tight junctions. Tight junctions are specialized regions of cell to cell contact; made up of network of strands to act as a molecular gasket for preventing the leakage of ions, water, etc. between cells. They are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Different tissues exhibit different Claudin composition.