Product: Chenodeoxycholic Acid
Chromogranin A Antibody (CHGA/765) [FITC] Summary
Immunogen |
Recombinant human chromogranin A protein
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Localization |
Finely granular cytoplasmic
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Marker |
Neuroendocrine Marker
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Specificity |
Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
|
Isotype |
IgG2a Kappa
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Clonality |
Monoclonal
|
Host |
Mouse
|
Gene |
CHGA
|
Purity |
Protein A or G purified
|
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Applications/Dilutions
Dilutions |
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Application Notes |
Optimal dilution of this antibody shomld be experimentally determined.
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Packaging, Storage & Formulations
Storage |
Store at 4C in the dark.
|
Buffer |
PBS
|
Preservative |
0.05% Sodium Azide
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Purity |
Protein A or G purified
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Alternate Names for Chromogranin A Antibody (CHGA/765) [FITC]
- betagranin (N-terminal fragment of chromogranin A)
- Betagranin
- Catestatin
- CGA
- CHGA
- Chromofungin
- chromogranin A (parathyroid secretory protein 1)
- Chromogranin A
- chromogranin-A
- Pancreastatin
- Parastatin
- Parathyroid Secretory Protein 1
- Pituitary Secretory Protein I
- SP-I