Chromogranin A Antibody (CHGA/765) – Azide and BSA Free

Product: Varenicline (Tartrate)

Chromogranin A Antibody (CHGA/765) – Azide and BSA Free Summary

Immunogen
Recombinant human chromogranin A protein
Localization
Finely granular cytoplasmic
Marker
Neuroendocrine Marker
Specificity
Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CHGA
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry : 0.5 – 1 ug/million cells in 0.1 ml
  • Immunohistochemistry-Paraffin : 0.5 – 1.0 ug/ml
  • CyTOF-ready
  • Immunofluorescence : 1 – 2 ug/ml
Application Notes
Hu-chromosome location: 14q32.12 Molecular weight of antigen: 68-75kDa Immunohistochemistry-Paraffin 0.5 – 1 ug/ml for 30 minutes at RT; Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10 – 20 min followed by cooling at RT for 20 minutes.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
No Preservative
Concentration
1.0 mg/ml
Purity
Protein A or G purified

Alternate Names for Chromogranin A Antibody (CHGA/765) – Azide and BSA Free

  • betagranin (N-terminal fragment of chromogranin A)
  • Betagranin
  • Catestatin
  • CGA
  • CHGA
  • Chromofungin
  • chromogranin A (parathyroid secretory protein 1)
  • Chromogranin A
  • chromogranin-A
  • Pancreastatin
  • Parastatin
  • Parathyroid Secretory Protein 1
  • Pituitary Secretory Protein I
  • SP-I

PMID: 23840801