Chorionic Gonadotropin alpha Chain (HCG alpha) Antibody (HCGa/53) – IHC-Prediluted Summary
| Immunogen |
Recombinant hCG alpha protein
|
| Localization |
Cytoplasmic, secreted
|
| Marker |
Pregnancy & Choriocarcinoma Marker
|
| Specificity |
This MAb reacts with a protein of ~13kDa, identified as alpha sub-unit of HCG. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the ? and ? subunits. The subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH).
|
| Isotype |
IgG1 Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
CGA
|
| Purity |
Protein A or G purified
|
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Applications/Dilutions
| Dilutions |
|
| Application Notes |
Hu-chromosome location: 6q12-q21
Molecular weight of antigen: ~13kDa Immunohistochemistry-Paraffin 1 – 2 ug/ml for 30 minutes at RT; No special pre-treatment is required for staining of formalin-fixed tissues. Note that HIER is NOT recommended for this antibody. |
Packaging, Storage & Formulations
| Storage |
Store at 4C.
|
| Buffer |
10mM PBS and 0.05% BSA
|
| Preservative |
0.05% Sodium Azide
|
| Purity |
Protein A or G purified
|
Alternate Names for Chorionic Gonadotropin alpha Chain (HCG alpha) Antibody (HCGa/53) – IHC-Prediluted
- alpha HCG
- CGA glycoprotein hormones, alpha polypeptide
- CGA
- CG-ALPHA
- Chorionic Gonadotropin alpha Chain
- FSHA
- GPHa
- GPHa1
- HCG
- LHA
- TSHA