Cdc20 Antibody (BA8) Summary
| Immunogen |
Peptide from the carboxy terminus of the protein.
|
| Isotype |
IgG2a
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| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
CDC20
|
| Purity |
Protein A or G purified
|
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|
Applications/Dilutions
| Dilutions |
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| Publications |
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Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS
|
| Preservative |
0.02% Sodium Azide
|
| Concentration |
1.0 mg/ml
|
| Purity |
Protein A or G purified
|
Alternate Names for Cdc20 Antibody (BA8)
- CDC20 cell division cycle 20 homolog (S. cerevisiae)
- CDC20 cell division cycle 20 homolog
- cell division cycle 20 homolog (S. cerevisiae)
- cell division cycle protein 20 homolog
- MGC102824
- p55CDCS. cerevisiae, homolog)
Background
CDC20 is an activating regulatory factor for the APC/C (anaphase promoting complex/cyclosome). It activates the ubiquitination activity of the APC/C. CDC20 confers a strict destruction-box (D-box) dependence on APC. Levels of CDC20, as well as its binding to APC, peak in mitosis and decrease drastically at early G1.