Carboxypeptidase E/CPE Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human Carboxypeptidase E. The exact sequence is proprietary.
|
| Localization |
Secreted
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
CPE
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
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| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
53 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Expected cross reactivity based on sequence homology: Chimpanzee (99%), Xenopus laevis (83%), Zebrafish (85%), Xenopus tropicalis (84%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
0.68 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for Carboxypeptidase E/CPE Antibody
- Carboxypeptidase E
- Carboxypeptidase H
- CPE
- CPH
- CPH-1
- EC 3.4.17
- EC 3.4.17.10
- Enkephalin convertase
- Prohormone-processing carboxypeptidase
Background
This gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes. [provided by RefSeq]