CXCL12/SDF-1 alpha Antibody Summary
| Immunogen |
E. coli-expressed human SDF-1α.
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
CXCL12
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Western blot analysis (0.5-1 ug/ml). Based on researchers feedback, it can also be used in immunofluorescence and neutralization (2-10 ug/ml). However, the optimal conditions should be determined individually.
|
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.2) and 30% Glycerol, 0.5% BSA.
|
| Preservative |
0.01% Thimerosal
|
| Purity |
Immunogen affinity purified
|
Alternate Names for CXCL12/SDF-1 alpha Antibody
- CXCL12 chemokine (C-X-C motif) ligand 12
- CXCL12/SDF-1 alpha
- IRH
- PBSF
- SCYB12
- SDF1 alpha
- SDF1
- SDF1a
- SDF1B
- TLSF
- TPAR1
Background
For background information on chemokines, see CXCL11 (SCYB11; MIM 604852). Stromal cell-derived factors 1-alpha and 1-beta are small cytokines that belong to the intercrine family, members of which activate leukocytes and are often induced by proinflammatory stimuli such as lipopolysaccharide, TNF (see MIM 191160), or IL1 (see MIM 147760). The intercrines are characterized by the presence of 4 conserved cysteines which form 2 disulfide bonds. They can be classified into 2 subfamilies. In the CC subfamily, which includes beta chemokine, the cysteine residues are adjacent to each other. In the CXC subfamily, which includes alpha chemokine, they are separated by an intervening amino acid. The SDF1 proteins belong to the latter group.[supplied by OMIM]