CPEB1 Antibody Summary
| Immunogen |
Peptide with sequence C-PLMRNQKNRDSS corresponding to C-Terminus according to NP_085097.3, NP_001073001.1, NP_001073002.1, NP_001073003.1.
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| Localization |
Cytoplasmic
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| Specificity |
This antibody is expected to recognise alle reported isoforms. Variants (NP_001073002.1; NP_001073003.1) encode the same isoform.
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| Clonality |
Polyclonal
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| Host |
Goat
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| Gene |
CPEB1
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
WB: Approx. 65-70 kDa band observed in human brain lysates (predicted MW of 65 kDa band according to NP_085097). Please note this band was always accompanied by a slightly stronger band at approx. 48 kDa and both bands could be blocked by incubation with the immunizing peptide.
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| Positive Control |
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| Publications |
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Reactivity Notes
Predicted cross-reactivity based on sequence identity: Bovine.
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
|
| Buffer |
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
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| Preservative |
0.02% Sodium Azide
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| Concentration |
0.5 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for CPEB1 Antibody
- CPEBCEBP
- CPE-binding protein 1
- CPE-BP1
- cytoplasmic polyadenylation element binding protein 1
- cytoplasmic polyadenylation element-binding protein 1
- FLJ13203
- h-CEBP
- hCPEB-1
- MGC34136
- MGC60106
Background
This gene encodes a member of the cytoplasmic polyadenylation element (CPE) binding protein family. This highly conserved protein binds to a specific RNA sequence called the CPE found in the 3 UTR of some mRNAs. Similar proteins in Xenopus and mouse function to induce cytoplasmic polyadenylation of dormant mRNAs with short polyA tails, resulting in their translation. Members of this protein family regulate translation of cyclin B1 during embryonic cell divisions. Multiple transcript variants encoding different isoforms have been found for this gene.