CLCN4 Antibody Summary
| Immunogen |
This CLC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 663-689 amino acids from the C-terminal region of human CLC4.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
CLCN4
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| Purity |
Ammonium sulfate precipitation
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Applications/Dilutions
| Dilutions |
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Reactivity Notes
Reacts with Human. Predicted to react with Mouse and Rat.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS
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| Preservative |
0.09% Sodium Azide
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| Purity |
Ammonium sulfate precipitation
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Alternate Names for CLCN4 Antibody
- chloride channel 4
- Chloride channel protein 4
- Chloride transporter ClC-4
- CLC4
- ClC-4
- ClC-4A
- H(+)/Cl(-) exchange transporter 4
- MGC163150
Background
The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. This gene is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I), which are both located on the human X chromosome at band p22.3. The physiological role of chloride channel 4 remains unknown but may contribute to the pathogenesis of neuronal disorders.