CELSR2 Antibody

Product: Pardoprunox (hydrochloride)

CELSR2 Antibody Summary

Immunogen
Synthetic 19 amino acid peptide from N-terminal extracellular domain of human CELSR2 / EGFL2.
Localization
Integral membrane protein
Specificity
Human CELSR2 / EGFL2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Clonality
Polyclonal
Host
Rabbit
Gene
CELSR2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 15 – 20 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gibbon (95%), Marmoset (95%), Monkey (89%), Mouse (84%), Rat (84%), Bovine (84%), Equine (84%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for CELSR2 Antibody

  • cadherin EGF LAG seven-pass G-type receptor 2
  • Cadherin family member 10
  • cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
  • CDHF10
  • CDHF10FLJ34118
  • CELSR2
  • EGFL2
  • EGFL2FLJ45143
  • EGF-like protein 2
  • EGF-like-domain, multiple 2
  • epidermal growth factor-like 2
  • Epidermal growth factor-like protein 2
  • Flamingo homolog 3
  • Flamingo1
  • FLJ45845
  • KIAA0279FLJ42737
  • MEGF3
  • MEGF3cadherin, EGF LAG seven-pass G-type receptor 2, flamingo (Drosophila) homolog
  • Multiple EGF-like domains protein 3
  • multiple epidermal growth factor-like domains 3
  • Multiple epidermal growth factor-like domains protein 3

Background

CELSR2 is an Orphan-U GPCR with an unknown ligand. CELSR2 expression has been documented in the developing mouse embryo. ESTs have been isolated from adrenal, B-cell/lung/testis, brain, breast, colon, embryo, heart, heart/melanocyte/uterus, kidney, nerve, skin, testis, and vessel libraries.

PMID: 8566162