CD99 Antibody (MEM-131) [PE] Summary
| Immunogen |
HPB-ALL human peripheral blood leukemia T-cell line
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| Specificity |
The antibody MEM-131 reacts with CD99R, an epitope restricted to a subset of CD99 molecule expressed on myeloid cells, NK cells and T lymphocytes. HLDA V; WS Code AS S020 HLDA V; WS Code T T-E2.02 HLDA V; WS Code T T-017
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| Isotype |
IgM
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
CD99
|
| Purity |
Protein A or G purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
The reagent is designed for Flow Cytometry analysis of human blood cells using 20 ul reagent / 100 ul of whole blood or 10^6 cells in a suspension.
|
Reactivity Notes
Cross-reacts with Human. Not yet tested in other species.
Packaging, Storage & Formulations
| Storage |
Store at 4C in the dark.
|
| Buffer |
TBS and 0.2% (w/v) high grade BSA (protease free)
|
| Preservative |
15mM Sodium Azide
|
| Purity |
Protein A or G purified
|
Notes
Store in the dark. Avoid prolonged exposure to light.
Alternate Names for CD99 Antibody (MEM-131) [PE]
- 12E7
- antigen identified by monoclonal antibodies 12E7, F21 and O13
- CD99 antigenY homolog
- CD99 molecule
- CD99
- E2 antigen
- HBA71
- MIC2 (monoclonal 12E7)
- MIC2
- MIC2Y
- MSK5X
- pilr-1
- PILR-L
- Protein MIC2
- surface antigen MIC2
- T-cell surface glycoprotein E2
Background
CD99 (E2, MIC2) is a transmembrane glycoprotein that is involved in regulation of T cell addhesive properties and programmed cell death distinct from typical apoptosis course. CD99 roles are specific to certain stages of T cell differentiation such as corticothymocytes. CD99R isoform expression is restricted in the haematopoietic system to T, NK and myeloid cells.