CD99 Antibody (DN16) Summary
| Immunogen |
Made to Human CD99
|
| Specificity |
Recognizes the human CD99 cell surface antigen, a 32kD glycoprotein expressed by all leucocytes. CD99 expression tends to be highest on immature cells. Functionally CD99 has been found to be involved in lymphocyte adhesion/aggregation and apoptosis.
|
| Isotype |
IgG1
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
CD99
|
| Purity |
Protein A or G purified
|
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|
Applications/Dilutions
| Dilutions |
|
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
Phosphate buffered saline
|
| Preservative |
0.1% Sodium Azide
|
| Concentration |
1.0 mg/ml
|
| Purity |
Protein A or G purified
|
Alternate Names for CD99 Antibody (DN16)
- 12E7
- antigen identified by monoclonal antibodies 12E7, F21 and O13
- CD99 antigenY homolog
- CD99 molecule
- CD99
- E2 antigen
- HBA71
- MIC2 (monoclonal 12E7)
- MIC2
- MIC2Y
- MSK5X
- pilr-1
- PILR-L
- Protein MIC2
- surface antigen MIC2
- T-cell surface glycoprotein E2
Background
CD99 is a 32kDa glycoprotein, which is thought to be involved in cell adhesion processes. Expression of CD99 is a characteristic of cells from Ewings sarcoma and primitive peripheral neuroectodermal tumors. However expression is also seen in certain normal cells such as pancreatic islet cells, cortical thymocytes, Sertoli cells and ovarian granulosa cells. Mature granulocytes express very little or no CD99.