CD3 zeta Antibody Summary
| Immunogen |
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CD3 zeta. The exact sequence is proprietary.
|
| Localization |
Membrane
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| Predicted Species |
Bovine (100%), Sheep (100%). Backed by our 100% Guarantee.
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| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
CD247
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
19 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
0.78 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for CD3 zeta Antibody
- CD247 antigen
- CD247 antigen, zeta subunit
- CD247 molecule
- CD247
- CD3 zeta
- CD3H
- CD3Q
- CD3z antigen, zeta polypeptide (TiT3 complex)
- CD3Z
- CD3ZT-cell receptor T3 zeta chain
- IMD25
- T3Z
- T-cell antigen receptor complex, zeta subunit of CD3
- T-cell surface glycoprotein CD3 zeta chain
- TCR Zeta Chain
- TCRZCD3-ZETA
Background
The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq]