CD3 epsilon Antibody (APA1/1) [PE] Summary
| Immunogen |
Purified human CD3 proteins isolated from thymus
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| Specificity |
The mouse monoclonal antibody APA1/1 recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T-cell activation. APA1/1 provides the earliest known marker for TCR-mediated T cell activation.
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| Isotype |
IgG1
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| Clonality |
Monoclonal
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| Host |
Mouse
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| Gene |
CD3E
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| Purity |
Protein A purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
This antibody is useful in Flow Cytometry, Immunoprecipitation, Western Blotting, Immunohistochemistry-frozen and Immunocytochemistry
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Reactivity Notes
Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.
Packaging, Storage & Formulations
| Storage |
Store at 4C in the dark.
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| Buffer |
PBS
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| Preservative |
0.05% Sodium Azide
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| Purity |
Protein A purified
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Alternate Names for CD3 epsilon Antibody (APA1/1) [PE]
- CD3 epsilon
- CD3e antigen
- CD3e antigen, epsilon polypeptide (TiT3 complex)
- CD3e molecule, epsilon (CD3-TCR complex)
- CD3e
- CD3-epsilon
- FLJ18683
- T3E
- T-cell antigen receptor complex, epsilon subunit of T3
- T-cell surface antigen T3/Leu-4 epsilon chain
- T-cell surface glycoprotein CD3 epsilon chain
- TCRE