Product: Dopamine (hydrochloride)
CD34 Antibody (HPCA1/763) [DyLight 405] Summary
Immunogen |
Recombinant full-length human HPCA1 protein
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Localization |
Cell surface
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Marker |
Hematopoietic Stem Cell & Endothelial Marker
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Specificity |
This MAb recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi s sarcoma, but with a lower specificity.
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Isotype |
IgG1 Kappa
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Clonality |
Monoclonal
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Host |
Mouse
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Gene |
CD34
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Purity |
Protein A or G purified
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Applications/Dilutions
Dilutions |
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Application Notes |
Optimal dilution of this antibody shomld be experimentally determined.
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Packaging, Storage & Formulations
Storage |
Store at 4C in the dark.
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Buffer |
50mM Sodium Borate
|
Preservative |
0.05% Sodium Azide
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Purity |
Protein A or G purified
|
Notes
Alternate Names for CD34 Antibody (HPCA1/763) [DyLight 405]
- CD34 antigenhematopoietic progenitor cell antigen CD34
- CD34 molecule
- CD34
- HPCA1