CD28 Antibody (PV-1)

Product: NMS-860

CD28 Antibody (PV-1) Summary

Immunogen
C57BL/6N mouse T cell lymphoma EL4 cell line
Specificity
Murine CD28
Isotype
IgG
Clonality
Monoclonal
Host
Armenian Hamster
Gene
CD28
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10 – 1:1000
  • Immunoprecipitation 1:10 – 1:500
  • In vitro assay

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
0.1M BBS (pH 8.2)
Preservative
No Preservative
Concentration
0.5 mg/ml
Purity
Protein A or G purified

Alternate Names for CD28 Antibody (PV-1)

  • CD28 antigen (Tp44)
  • CD28 antigen
  • CD28 molecule
  • CD28
  • MGC138290
  • T-cell-specific surface glycoprotein CD28
  • Tp44

Background

CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes, and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. (1-4) CD28 is a ligand for CD80/B7-1 and CD86/B7-2 on B cells and other antigen presenting cells, and plays an important role in the interaction between T cells and B cells. (5) CD28 is a co-stimulatory receptor involved in many, but not all, T-cell independent immune responses. (6-9)

PMID: 24877132