CD117/c-kit Antibody (6G12) Summary
| Immunogen |
KIT (NP_000213, 41 a.a. – 140 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. PGKSDLIVRVGDEIRLLCTDPGFVKWTFEILDETNENKQNEWITEKAEATNTGKYTCTNKHGLSNSIYVFVRDPAKLFLVDRSLYGKEDNDTLVRCPLTD
|
| Marker |
Hematopoietic Stem Cell Marker
|
| Specificity |
KIT – v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
|
| Isotype |
IgG2b Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
KIT
|
| Purity |
IgG purified
|
| Innovators Reward |
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.
|
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for CD117/c-kit Antibody (6G12)
- CD117 antigen
- CD117
- ckit
- c-kit
- EC 2.7.10
- EC 2.7.10.1
- KIT
- PBT
- piebald trait
- Proto-oncogene c-Kit
- proto-oncogene tyrosine-protein kinase Kit
- SCF R
- SCFRmast/stem cell growth factor receptor
- soluble KIT variant 1
- Tyrosine-protein kinase Kit
- v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
- v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein
Background
This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.