Product: GTS-21 (dihydrochloride)
CCR6 Antibody Summary
| Immunogen |
Synthetic peptide: YFVSVNTSYYSVDSEMLLCSLQEVRQFSR, corresponding to amino acids 18-46 of Human CCR6.
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| Localization |
Integral membrane protein
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| Clonality |
Polyclonal
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| Host |
Goat
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| Gene |
CCR6
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Positive Control |
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Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
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| Buffer |
10mM KHPO4, 0.14M NaCl and 1.0 mg/ml BSA
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| Preservative |
0.1% Sodium Azide
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| Concentration |
1.0 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for CCR6 Antibody
- BN-1
- CC-CKR-6
- CCR6
- CCR-6
- CD196 antigen
- CD196
- chemokine (C-C motif) receptor 6
- CKR-L3G-protein coupled receptor 29
- CKRL3LARC receptor
- CMKBR6STRL22
- DRY6
- GPR29
- GPR29C-C CKR-6
- GPR-CY4
- GPRCY4DRY-6
- lymphocyte, 22
- STRL22
Background
CCR6 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein coupled receptors. It is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP 3 alpha). This receptor has been shown to be important for B lineage maturation and antigen driven B cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. CCR6 has been reported to be expressed in intestine, colon, liver, lymph node, spleen, lung, blood, umbilical cord, placenta, skin, and pancreas. It has also been reported to be expressed in lymphocytes, T cells, and B cells.