CCK-A R Antibody (377251) [Alexa Fluor® 405] Summary
| Specificity |
Detects human CCK‑A R. Stains human CCK-A R transfectants but not irrelevant transfectants.
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| Isotype |
IgG2a
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| Clonality |
Monoclonal
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| Host |
Mouse
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| Gene |
CCKAR
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Applications/Dilutions
| Dilutions |
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| Application Notes |
Flow Cytometry: Please use 0.25-1 ug of conjugated antibody per 10e6 cells.
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Packaging, Storage & Formulations
| Storage |
Store the unopened product at 2 – 8 °C. Do not use past expiration date.
|
| Buffer |
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
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| Preservative |
0.09% Sodium Azide
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| Concentration |
Please see the vial label for concentration. If unlisted please contact technical services.
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Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for CCK-A R Antibody (377251) [Alexa Fluor® 405]
- CCK1R
- CCK1-R
- CCK-A R
- CCK-A receptor
- CCK-A
- CCKAR
- CCK-AR
- CCKRA
- cholecystokinin A receptor
- cholecystokinin receptor type A
- cholecystokinin type-A receptor
- Cholecystokinin-1 receptor
Background
Cholecystokinin A Receptor (CCK-A R) is one of two 7TM receptors for cholecystokinin peptide hormones. This GPCR is involved in gallbladder contraction, insulin secretion, and central nervous system function. CCK-A R has been implicated in pancreatic tumorigenesis as well as the pathogenesis of eating disorders and drug addiction. Human CCK-A R shares 89% aa sequence identity with mouse and rat CCK-A R.