CCK-A R Antibody (377251) Summary
| Immunogen |
NS0 mouse myeloma cell line transfected with human CCK‑A R
Met1-Gln428 Accession # P32238 |
| Specificity |
Detects human CCK‑A R. Stains human CCK-A R transfectants but not irrelevant transfectants.
|
| Source |
N/A
|
| Isotype |
IgG2a
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
CCKAR
|
| Purity |
Protein A or G purified from hybridoma culture supernatant
|
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Applications/Dilutions
| Dilutions |
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Packaging, Storage & Formulations
| Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
|
| Buffer |
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
|
| Preservative |
No Preservative
|
| Concentration |
LYOPH
|
| Purity |
Protein A or G purified from hybridoma culture supernatant
|
| Reconstitution Instructions |
Reconstitute at 0.5 mg/mL in sterile PBS.
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Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for CCK-A R Antibody (377251)
- CCK1R
- CCK1-R
- CCK-A R
- CCK-A receptor
- CCK-A
- CCKAR
- CCK-AR
- CCKRA
- cholecystokinin A receptor
- cholecystokinin receptor type A
- cholecystokinin type-A receptor
- Cholecystokinin-1 receptor
Background
The physiologic actions of the cholecystokinin (CCK) family of peptide hormones are mediated through two classes of G protein-coupled receptors GPCR), CCK-A R and CCK-B R. CCK-A R is a 428 amino acid protein with 7 putative transmembrane domains. This GPCR is involved in gall bladder contraction, insulin secretion, and has also been described in specific regions of the central nervous system. CCK-A R has been implicated in pancreatic tumorigenesis as well as the pathogenesis of eating disorders and drug addiction.