CBX1 Antibody (5A3) Summary
| Immunogen |
Purified recombinant fragment of human CBX1 expressed in E. Coli.
|
| Isotype |
IgG1
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
CBX1
|
| Purity |
Unpurified
|
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|
Applications/Dilutions
| Dilutions |
|
Reactivity Notes
Human, Primate
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
Ascites
|
| Preservative |
0.03% Sodium Azide
|
| Purity |
Unpurified
|
Alternate Names for CBX1 Antibody (5A3)
- CBXM31HP1-BETA
- chromobox homolog 1 (Drosophila HP1 beta)
- chromobox homolog 1 (HP1 beta homolog Drosophila )
- chromobox homolog 1
- chromobox protein homolog 1
- Heterochromatin protein 1 homolog beta
- heterochromatin protein 1-beta
- heterochromatin protein p25 beta
- Heterochromatin protein p25
- HP1 beta homolog
- HP1 beta
- HP1Hsbeta
- HP1Hs-beta
- MOD1
- Modifier 1 protein
- p25beta
Background
This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq]