CASC3 Antibody Summary
| Immunogen |
Maps to a region between residue 225 and 275 of humancancer susceptibility candidate 3 using the numbering given in entry NP_031385.2
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
CASC3
|
| Purity |
Immunogen affinity purified
|
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Applications/Dilutions
| Dilutions |
|
| Application Notes |
This antibody is useful in Immunoprecipitation. Western Blot is not recommended.
|
Reactivity Notes
Human
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
Tris-Citrate/Phosphate (pH 7.0 – 8.0)
|
| Preservative |
0.09% Sodium Azide
|
| Concentration |
1.0 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for CASC3 Antibody
- barentsz
- Btz
- cancer susceptibility candidate 3
- Cancer susceptibility candidate gene 3 protein
- metastatic lymph node 51
- Metastatic lymph node gene 51 protein
- MLN 51
- MLN51BTZ
- Protein barentsz
- protein CASC3
Background
The product of this gene is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles.