Bub1 Antibody (2F9) Summary
| Immunogen |
BUB1 (AAH28201, 1 a.a. – 130 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MDTPENVLQMLEAHMQSYKGNDPLGEWERYIQWVEENFPENKEYLITLLEHLMKEFLDKKKYHNDPRFISYCLKFAEYNSDLHQFFEFLYNHGIGTLSSPLYIAWAGHLEAQGELQHASAVLQRGIQNQA
|
| Specificity |
BUB1 – BUB1 budding uninhibited by benzimidazoles 1 homolog (yeast)
|
| Isotype |
IgG1 Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
BUB1
|
| Purity |
IgG purified
|
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|
Applications/Dilutions
| Dilutions |
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| Application Notes |
Antibody reactivity against cell lysate, transfected lysate and recombinant protein for WB. It has been used for ELISA.
|
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Bub1 Antibody (2F9)
- BUB1 budding uninhibited by benzimidazoles 1 homolog
- Bub1
- BUB1Amitotic checkpoint serine/threonine-protein kinase BUB1
- BUB1L
- budding uninhibited by benzimidazoles 1 (yeast homolog)
- budding uninhibited by benzimidazoles 1 homolog (yeast)
- EC 2.7.11.1
- hBUB1mitotic spindle checkpoint kinase
- putative serine/threonine-protein kinase
Background
This gene encodes a kinase involved in spindle checkpoint function. The kinase functions in part by phosphorylating a member of the miotic checkpoint complex and activating the spindle checkpoint. Mutations in this gene have been associated with aneuploidy and several forms of cancer.