Blood Group Lewis b Antibody (2-25LE)

Product: Icatibant

Blood Group Lewis b Antibody (2-25LE) Summary

Immunogen
Mucin isolated by size exclusion chromatography from an ovarian cyst fluid (pure endocervical type according to the Fenoglios classification).
Specificity
The antibody 2-25LE reacts with Lewisb blood group antigen, a carbohydrate determinant carried on both glycolipids and glycoproteins, detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
FUT3
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:1000
  • ELISA 1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 5 – 10 ug/ml
Application Notes
Purity is > 95% (by SDS-PAGE). Heat mediated antigen retrieval (sodium citrate); mAb incubation 1 hour / RT; detection DAB
Publications
Read Publications using NB500-526.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (approx. pH 7.4)
Preservative
15mM Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein A purified

Alternate Names for Blood Group Lewis b Antibody (2-25LE)

  • alpha-(1,3/1,4)-fucosyltransferase
  • Blood group Lewis alpha-4-fucosyltransferase
  • CD174
  • EC 2.4.1
  • EC 2.4.1.65
  • FT3B
  • fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
  • Fucosyltransferase 3
  • Fucosyltransferase III
  • FucT-III
  • galactoside 3(4)-L-fucosyltransferase
  • LEfucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood groupincluded)
  • Les
  • Lewis FT
  • MGC131739

Background

The antibody 2-25LE reacts with Lewisb blood group antigen, a carbohydrate determinant carried on both glycolipids and glycoproteins, detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals.

PMID: 18434375