B-Myb Antibody

Product: Amonafide

B-Myb Antibody Summary

Immunogen
Peptide with sequence C-QEKARQLLGRLKPSH corresponding to C-Terminus according to NP_002457.1.
Clonality
Polyclonal
Host
Goat
Gene
MYBL2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 0.1 – 0.3 ug/ml
  • Peptide ELISA Detection limit 1:32000
Application Notes
WB: Approx. 100 kDa band observed in rat stomach lysates (calculated MW of 78.8 kDa band according to human NP_002457.1).
Positive Control
B-Myb Lysate (NBL1-13412)
Stomach Lysate (NB820-59719)
Publications
Read Publication using NB100-53779.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Human, Mouse, Canine, Porcine, Bovine.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for B-Myb Antibody

  • B-MYB
  • BMYBMGC15600
  • Myb-like protein 2
  • myb-related protein B
  • v-myb avian myeloblastosis viral oncogene homolog-like 2
  • v-myb myeloblastosis viral oncogene homolog (avian)-like 2

Background

The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Transcript variants may exist for this gene, but their full-length natures have not been determined.

PMID: 12537482