BRM Antibody

Product: Deferoxamine (mesylate)

BRM Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 100 and 150 of human SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 using the numbering given in entry CAA51407.1 (GeneID 6595).
Predicted Species
Mouse (100%), Rat (100%), Porcine (100%), Primate (100%), Turkey (100%), Bovine (100%), Monkey (100%), Chicken (100%), Xenopus (100%), Canine (100%), Equine (100%). Backed by our 100% Guarantee.
Clonality
Polyclonal
Host
Rabbit
Gene
SMARCA2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunoprecipitation 2 – 5 ug/mg lysate

Reactivity Notes

Based on 100% sequence identity, this antibody is predicted to react with X. laevis, X. tropicalis, Panda, Orangutan, Rhesus Monkey, Gorilla, Duckbill platypus, Tasmanian devil, White-tufted-ear marmoset, African elephant and Zebra finch.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for BRM Antibody

  • ATP-dependent helicase SMARCA2
  • BAF190B
  • BRG1-associated factor 190B
  • BRMFLJ36757
  • EC 3.6.1
  • EC 3.6.4.-
  • global transcription activator homologous sequence
  • hBRMMGC74511
  • hSNF2a
  • probable global transcription activator SNF2L2
  • Protein brahma homolog
  • SNF2
  • SNF2/SWI2-like protein 2
  • SNF2A
  • SNF2-alpha
  • SNF2L2BAF190
  • SNF2LA
  • SNF2-like 2
  • Sth1p
  • subfamily a, member 2
  • sucrose nonfermenting 2-like protein 2
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin
  • SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2
  • SWI/SNF-related matrix-associated actin-dependent regulator of chromatinsubfamily A member 2
  • SWI2

Background

The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Two transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism.

PMID: 25573298