BRAF35 Antibody Summary
| Immunogen |
Residues 31-50 [KQERGEGPRA GEKGSHEEEP] of the human structural DNA-binding protein BRAF35.
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| Specificity |
BRAF35
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
HMG20B
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
This antibody is useful for Western blot.
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| Positive Control |
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Reactivity Notes
Reacts with human. 80% sequence identity with mouse protein.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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| Buffer |
PBS
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| Preservative |
0.02% Sodium Azide
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| Concentration |
1 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for BRAF35 Antibody
- BRAF35Sox-like transcriptional factor
- high-mobility group 20B
- HMG domain-containing protein 2
- HMG domain-containing protein HMGX2
- HMGX2FLJ26127
- HMGXB2member 1-related
- SMARCE1R
- SMARCE1-related protein
Background
Mutations of the human BRCA2 gene confer susceptibility to breast cancer. A structural DNA binding component has been identified and is designated as BRCA2-Associated Factor 35 (BRAF35). There is a close association of the BRAF35/BRCA2 complex with condensed chromatin coincident with histone H3 phosphorylation. Experimental evidence suggests a role for the BRCA2/BRAF35 complex in the modulation of cell cycle progression.