BPNT1 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human BPNT1. The exact sequence is proprietary.
|
| Predicted Species |
Rat (94%), Bovine (93%). Backed by our 100% Guarantee.
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
BPNT1
|
| Purity |
Immunogen affinity purified
|
| Innovators Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
|
Applications/Dilutions
| Dilutions |
|
Reactivity Notes
Expected cross reactivity based on sequence homology: Chicken (83%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
0.7 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for BPNT1 Antibody
- 3(2), 5-bisphosphate nucleotidase 1,3(2)5-bisphosphate nucleotidase 1
- Bisphosphate 3-nucleotidase 1
- BPntase
- EC 3.1.3
- EC 3.1.3.7
- PAP-inositol-1,4-phosphatase
- PIP
Background
BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntases physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.