BMPR-IB/ALK-6 Antibody (3A8) Summary
| Immunogen |
BMPR1B (AAH47773, 14 a.a. – 103 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. KKEDGESTAPTPRPKVLRCKCHHHCPEDSVNNICSTDGYCFTMIEEDDSGLPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERNECN
|
| Specificity |
BMPR1B – bone morphogenetic protein receptor, type IB
|
| Isotype |
IgG1 Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
BMPR1B
|
| Purity |
IgG purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactivity against transfected lysate and recombinant protein for WB. It has been used for ELISA.
|
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for BMPR-IB/ALK-6 Antibody (3A8)
- activin receptor-like kinase 6
- ALK-6
- ALK6CDw293
- BMP type-1B receptor
- BMPR1B
- BMPR-1B
- BMPRIB
- BMPR-IB
- bone morphogenetic protein receptor type-1B
- bone morphogenetic protein receptor, type IB
- CDw293 antigen
- CDw293
- EC 2.7.11
- EC 2.7.11.30
- serine/threonine receptor kinase
Background
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension.