BCS1L Antibody (5F3) Summary
| Immunogen |
BCS1L (NP_004319 320 a.a. – 418 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. ASTEARIVFMTTNHVDRLDPALIRPGRVDLKEYVGYCSHWQLTQMFQRFYPGQAPSLAENFAEHVLRATNQISPAQVQGYFMLYKNDPVGAIHNAESLR
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| Specificity |
BCS1L – BCS1-like (yeast)
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| Isotype |
IgG1 Kappa
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| Clonality |
Monoclonal
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| Host |
Mouse
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| Gene |
BCS1L
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| Purity |
IgG purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
Antibody reactivity against transfected lysate and recombinant protein for WB. It has been used for ELISA.
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| Publications |
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
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| Buffer |
PBS (pH 7.4)
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| Preservative |
No Preservative
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| Purity |
IgG purified
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Notes
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for BCS1L Antibody (5F3)
- BCS
- BCS1 (yeast homolog)-like
- BCS1
- BCS1-like (S. cerevisiae)
- BCS1-like (yeast)
- BCS1-like protein
- BJSGRACILE
- FLNMS
- h-BCS
- h-BCS1
- mitochondrial chaperone BCS1
- mitochondrial complex III assembly
- PTD
Background
This gene encodes a homolog of the S. cerevisiae bcs1 protein which is involved in the assembly of complex III of the mitochondrial respiratory chain. The encoded protein does not contain a mitochondrial targeting sequence but experimental studies confirm that it is imported into mitochondria. Mutations in this gene are associated with mitochondrial complex III deficiency and the GRACILE syndrome. Two alternatively spliced transcripts encoding the same protein have been described.