Product: Ivabradine (D8 hydrochloride)
BANF1 Antibody Summary
| Immunogen |
Antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human BANF1. The immunogen is located within the last 50 amino acids of BANF1.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
BANF1
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Control Peptide |
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Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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| Buffer |
PBS
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| Preservative |
0.02% Sodium Azide
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| Concentration |
1 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for BANF1 Antibody
- BAFMGC111161
- barrier to autointegration factor 1
- barrier-to-autointegration factor
- BCRG1
- BCRP1
- Breakpoint cluster region protein 1
- D14S1460
Background
Barrier-to-autointegration factor 1 (BANF1) is a conserved chromatin protein that non-specifically binds double-stranded DNA. BANF1 also interacts with a family of nuclear proteins that include LAP2, emerin, and MAN1. It is also a host cell component of retroviral pre-integration complexes (PICs), including that of HIV. BANF1 will bind to p55 Gag (the structural precursor of HIV-1 virions) as well as its cleaved product matrix. In addition to being a host cell component of the PIC, it is thought that BANF1 is also present at low levels in incoming virions, and thus might contribute to the assembly or activity of HIV-1 PICs through direct binding to matrix as well as DNA. Despite its predicted molecular weight, BANF1 often migrates at a higher size in SDS-PAGE.