ATP2C1 Antibody (4G12) Summary
| Immunogen |
Purified recombinant fragment of ATP2C1 expressed in E. Coli.
|
| Isotype |
IgG1
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
ATP2C1
|
| Purity |
Unpurified
|
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|
Applications/Dilutions
| Dilutions |
|
Reactivity Notes
Human, Monkey
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
Ascites
|
| Preservative |
0.03% Sodium Azide
|
| Purity |
Unpurified
|
Alternate Names for ATP2C1 Antibody (4G12)
- ATPase, Ca++ transporting, type 2C, member 1
- BCPM
- benign chronic pemphigus (Hailey-Hailey disease)
- Ca(2+)-sequestering
- calcium-transporting ATPase type 2C member 1
- EC 3.6.3
- HHD
- hSPCA1
- HUSSY-28
- PMR1L
- secretory pathway Ca2+/Mn2+ ATPase 1
Background
The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium. Defects in this gene cause Hailey-Hailey disease, an autosomal dominant disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.