ARFGAP3 Antibody

Product: TOK-001

ARFGAP3 Antibody Summary

Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ARFGAP3. The exact sequence is proprietary.
Localization
Cytoplasm, Golgi apparatus membrane
Predicted Species
Mouse (92%), Rat (92%), Primate (100%), Bovine (92%), Chicken (92%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ARFGAP3
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunocytochemistry/Immunofluorescence 1:100-1:1000

Reactivity Notes

Expected cross reactivity based on sequence homology: Xenopus laevis (85%), Xenopus Tropicalis (85%), Rhesus Monkey (100%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
Preservative
0.01% Thimerosal
Concentration
0.42 mg/ml
Purity
Immunogen affinity purified

Alternate Names for ARFGAP3 Antibody

  • ADP-ribosylation factor GTPase activating protein 1
  • ADP-ribosylation factor GTPase activating protein 3
  • ADP-ribosylation factor GTPase-activating protein 3
  • ARF GAP 3
  • ARFGAP1
  • FLJ45618

Background

The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene. [provided by RefSeq]

PMID: 28270602