AP-2 beta/TFAP2B Antibody

Product: Cenicriviroc

AP-2 beta/TFAP2B Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human AP2 beta. The exact sequence is proprietary.
Localization
Nucleus
Predicted Species
Mouse (100%), Porcine (99%), Chicken (99%), Bovine (100%), Zebrafish (94%), Xenopus (99%), Canine (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TFAP2B
Purity
Immunogen affinity purified
Innovators Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Learn about the Innovators Reward

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunoprecipitation 1:100-1:500
Application Notes
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
50 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Xenopus laevis (99%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
Preservative
0.01% Thimerosal
Concentration
0.95 mg/ml
Purity
Immunogen affinity purified

Alternate Names for AP-2 beta/TFAP2B Antibody

  • activating enhancer binding protein 2 beta
  • Activating enhancer-binding protein 2-beta
  • AP2 beta
  • AP-2 beta
  • AP-2B
  • AP2-B
  • AP2-beta
  • CHAR
  • MGC21381
  • TFAP2B
  • transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
  • transcription factor AP-2 beta (activating enhancer-binding protein 2 beta)
  • transcription factor AP-2-beta

Background

This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives. [provided by RefSeq]

PMID: 10774780