AP2M1 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human AP2M1. The exact sequence is proprietary.
|
| Localization |
Cell membrane; Membrane; coated pit
|
| Predicted Species |
Rat (100%), Porcine (98%), Primate (99%), Chicken (98%), Monkey (98%), Bovine (100%), Xenopus (98%), Canine (100%). Backed by our 100% Guarantee.
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
AP2M1
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
50 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Xenopus laevis (98%), Rhesus Monkey (98%), Chimpanzee (99%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for AP2M1 Antibody
- Adaptin-mu2
- adaptor-related protein complex 2, mu 1 subunit
- AP-2 mu chain
- Clathrin assembly protein complex 2 medium chain
- clathrin coat adaptor protein AP50
- Clathrin coat assembly protein AP50
- Clathrin coat-associated protein AP50
- clathrin-associated/assembly/adaptor protein, medium 1
- HA2 50 kDa subunit
- KIAA0109
- mu subunit
- Plasma membrane adaptor AP-2 50 kDa protein
- plasma membrane adaptor AP-2 50kDA protein
Background
This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]