AK3 Antibody (SJB3-36) Summary
| Immunogen |
Recombinant human AK3 (adenylaste kinase isozyme 3) purified from E. coli
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| Specificity |
Anti-human AK3 mAb, clone SJB3-36, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human AK3 protein. Clone SJB3-36 is specific against AK3.
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| Isotype |
IgG1
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| Clonality |
Monoclonal
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| Host |
Mouse
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| Gene |
AK3
|
| Purity |
Protein G purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
The antibody has been tested by ELISA, Western blot and immunohistochemistry-Paraffin/Frozen analysis to assure specificity and reactivity.
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Reactivity Notes
This antibody is reactive against Human.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4) and 10% Glycerol
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| Preservative |
0.02% Sodium Azide
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| Concentration |
1.0 mg/ml
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| Purity |
Protein G purified
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Alternate Names for AK3 Antibody (SJB3-36)
- Adenylate kinase 3 alpha-like 1
- adenylate kinase 3 like 1
- adenylate kinase 3adenylate kinase 6
- AK 3
- AK6
- AKL3L
- AKL3L1
- EC 2.7.4
- EC 2.7.4.10
- FIX
- GTP:AMP phosphotransferase, mitochondrial
Background
Adenylate kinase (AK; adenosine triphosphate-adenosine monophosphate [ATP-AMP] phospho-transferase, EC 2.7.4.3) is a ubiquitous monomeric enzyme involved energy metabolism of prokaryotic and eukaryotic cells. Three isozymes (AK1, AK2 and AK3) are characterized in vertebrates. AK1 is present in the cytosol of skeletal muscle, brain, and erythrocyte, while AK2 is localized in the intermembrane space of mitochondria of liver, kidney, spleen and heart. AK3, called GTP:AMP phosphotransferase, exists in the mitochondrial matrix of liver and heart. These isozymes contribute to homeostasis of the adenine nucleotide composition in the cell.