AIP/ARA9 Antibody

Product: Bicyclomycin benzoate

AIP/ARA9 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human ARA9. The exact sequence is proprietary.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
AIP
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunocytochemistry/Immunofluorescence 1:100-1:1000
  • Immunohistochemistry 10 – 1:500
  • Immunohistochemistry-Paraffin 1:100-1:1000

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 20% Glycerol
Preservative
0.01% Thimerosal
Concentration
1.01 mg/ml
Purity
Immunogen affinity purified

Alternate Names for AIP/ARA9 Antibody

  • ARA9
  • FKBP16
  • FKBP37
  • SMTPHN
  • XAP2
  • XAP-2

Background

The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus. [provided by RefSeq]

PMID: 12825930

AIP/ARA9 Antibody

Product: Chebulinic acid

AIP/ARA9 Antibody Summary

Immunogen
Peptide with sequence C-EARIRQKDEEDKAR corresponding to C-Terminus according to NP_003968.1.
Epitope
EARIRQKDEEDKAR
Clonality
Polyclonal
Host
Goat
Gene
AIP
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 0.02 – 0.06 ug/ml
  • Peptide ELISA Detection limit 1:64000
Application Notes
WB: Approx. 37 kDa band observed in lysates of NIH/3T3 (calculated MW of 37.7 kDa band according to human NP_003968.1 and 37.6 kDa band according to mouse NP_057875.1). In transfected HEK293 transiently expressing ARA9 a band of approx. 42 kDa is observed. This band is not observed in the non-transfected HEK293.
Positive Control
AIP/ARA9 Lysate (NBL1-07415)
Publications
Read Publication using NB100-61656.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Rat, Canine.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for AIP/ARA9 Antibody

  • ARA9
  • FKBP16
  • FKBP37
  • SMTPHN
  • XAP2
  • XAP-2

Background

Atrophin-interacting-protein 1 (AIP1) contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. The protein encoded by this gene interacts with atrophin-1. This encoded protein is characterized by two WW domains, a guanylate kinase-like domain, and multiple PDZ domains. It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family. This protein is brain specific, where it appears to be widely expressed in both neurons and glia.

PMID: 8662940