AGAP2 Antibody Summary
| Immunogen |
Recombinant human AGAP2 / PIKE.
|
| Specificity |
Amino acids 1-836 of human AGAP2 protein.
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
AGAP2
|
| Purity |
Protein A purified
|
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|
Applications/Dilutions
| Dilutions |
|
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.2)
|
| Preservative |
0.01% Sodium Azide
|
| Concentration |
1.0 mg/ml
|
| Purity |
Protein A purified
|
Alternate Names for AGAP2 Antibody
- AGAP-2
- ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
- arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2
- centaurin, gamma 1
- centaurin-gamma-1
- CENTG1
- cnt-g1
- FLJ16430
- GGAP2
- GTP-binding and GTPase activating protein 2
- GTP-binding and GTPase-activating protein 2
- KIAA0167
- Phosphatidylinositol-3-kinase enhancer
- phosphoinositide 3-kinase enhancer
- PIKEArf GAP with GTP-binding protein-like, ANK repeat and PH domains 2
Background
AGAP2 (also known as centaurin-gamma1, ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2, Phosphatidyl-inositol-3-kinase enhancer, PIKE, GTP-binding and GTPase activating protein 2 and GGAP2) is a GTPase activating protein that inactivates Arf. The expression of AGAP2 is amplified in human glioblastoma cells. AGAP2 protein binds to and activates the protein kinase Akt and prevents apoptosis of cancer cells. AGAP2 also increases motility and invasive activity of cancer cells. AGAP2 may serve as a diagnostic and therapeutic target of human cancer.