AF9 Antibody Summary
| Immunogen |
The immunogen recognized by this antibody maps to a region between residues 250 and 300 of human ALL1 Fused Gene from Chromosome 9 Protein using the numbering given in entry NP_004520.1 (GeneID 4300).
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
MLLT3
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Positive Control |
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Reactivity Notes
Human
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
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| Buffer |
Tris-Citrate/Phosphate (pH 7.0 – 8.0)
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| Preservative |
0.09% Sodium Azide
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| Concentration |
1.0 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for AF9 Antibody
- AF-9
- AF9myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog);translocated to, 3
- ALL1-fused gene from chromosome 9 protein
- myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocatedto, 3
- myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila);translocated to, 3
- Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein
- protein AF-9
- YEATS domain-containing protein 3
- YEATS3FLJ2035
Background
The human AF9 gene is one of the most common fusion partner genes with the MLL (mixed lineage leukemia) gene resulting in AF9/MLL translocations and leukemogenesis. AF9 is highly homologous to the gene product of ENL, another common MLL fusion partner gene. The function of AF9 is not known but through studies of ENL it is proposed to be a nuclear transactivating factor. AF9 is also known as ALL1 Fused Gene from Chromosome 9 Protein, MLLT3, Myeloid/Lymphoid or Mixed-Lineage Leukemia Translocated 3, YEATS3, and FLJ2035.