ADNP Antibody Summary
| Immunogen |
Human 114 kDa ADNP protein.
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| Specificity |
Reacts with human 114 kDA hADNP protein.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
ADNP
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
This antibody is useful for Western Blotting, use at a dilution of 1:500-1:1000. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry-frozen and paraffin.
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| Positive Control |
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Reactivity Notes
Human.
Others not specified
Others not specified
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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| Buffer |
PBS
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| Preservative |
0.02% Sodium Azide
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| Concentration |
1 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for ADNP Antibody
- Activity-dependent neuroprotective protein
- activity-dependent neuroprotector homeobox
- activity-dependent neuroprotector
- ADNP homeobox 1
- ADNP
- ADNP1
- ADNP1KIAA0784activity-dependent neuroprotector homeobox protein
Background
The activity-dependent neuroprotective protein (hADNP) gene is frequently amplified in many neoplasias, including breast, bladder, ovarian, pancreatic, and colon cancers. hADNP mRNA is abundantly expressed in distinct normal tissues, and high expression levels were encountered in malignant cells. hADNP is implicated in maintaining cell survival, perhaps through modulation of p53.