Product: Phorbol 12-myristate 13-acetate
ADAMTS13 Antibody Summary
| Immunogen |
Synthetic peptide derived from Nter domain of ADAM-TS 13 protein
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| Specificity |
Reacts specifically with human 153 kDa ADAM-TS 13 protein
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
ADAMTS13
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| Purity |
Unpurified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
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| Theoretical MW |
154 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
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| Publications |
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Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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| Buffer |
Antiserum
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| Preservative |
No Preservative
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| Concentration |
LYOPH
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| Purity |
Unpurified
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| Reconstitution Instructions |
Reconstitute with 0.2 ml distilled water.
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Alternate Names for ADAMTS13 Antibody
- A disintegrin and metalloproteinase with thrombospondin motifs 13
- a disintegrin-like and metalloprotease (reprolysin type) with thrombospondintype 1 motif, 13
- ADAM metallopeptidase with thrombospondin type 1 motif, 13
- ADAMTS13
- ADAM-TS13
- ADAMTS-13
- DKFZp434C2322
- EC 3.4.24.14
- EC 3.4.24.82
- EC 3.4.24.87
- FLJ42993
- MGC118899
- MGC118900
- TTP
- TTPADAM-TS 13
- vWF-cleaving protease
- vWF-CP
- vWF-CPC9orf8
- VWFCPvon Willebrand factor-cleaving protease
Background
Von Willebrand Factor (VWF) was previously known as Factor VIII related antigenis. VWF is synthesized exclusively by endothelial cells and megakaryocytes, and stored in the intracellular granules or constitutively secreted into plasma. This glycoprotein functions as both an antihemophilic factor carrier and a platelet vessel wall mediator in the blood coagulation system. Important in the maintenance of homeostasis, it participates in platelet vessel wall interactions by forming a noncovalent complex with coagulation factor VIII at the site of vascular injury. The Von Willebrand factor has functional binding domains to platelet glycoprotein Ib, glycoprotein IIb/IIIa, collagen and heparin. Mutations in this gene or deficiencies in this protein result in Von Willebrands disease. VWD is characterized by frequent bleeding (gingival, minor skin quantitative lacerations, menorrhagia, etc.).