The strains have solitary knockouts of the snoRNAs snR10, snR34, snR37, snR42, and snR46 which together pseudouridylate 6 rRNA residues in the PTC of the yeast ribosome, with snR34 modifying two of these residues
In fact, disruption/deletion of pseudouridine synthase proteins accountable for modification of only two or 3 residues in E. coli did…